Composition:
Each tablet contains:
Echinacea purpurea extract ……………………. 300 mg
Piper betle extract ……………………………………….. 20 mg
Piper nigrum extract …………………………………… 20 mg
Zingiber officinale extract ………………………….. 20 mg
Solanum indicum extract …………………………… 20 mg

Echinacea purpurea is the most potent ancient herbal medicine for natural immunity, anti-inflammatory and antiallergy. This plant is cultivated in Shan State, Myanmar.

Pharmacological actions:
1. Immunostimulating effect
Echinacea stimulates the non-specific immune system, resulting an increase in phagocytosis. Arabinogalactan, a highly purified polysaccharides from the constituents of Echinacea is effective in activating macrophage cytotoxic actions against micro-organisms. In addition, the polysaccharides have an anti-hyaluronidase action thus may be lessened the spread of infectious agent in the body.

2. Antiviral effect
Echinacea has some short term viral resistance against influenza, herpes, vesicular stomatitis virus and others. It inhibits the induction of multiple proinflammatory cytokines by respiratory viruses.

3. Anti-inflammatory effect
The constituents of Echinacea contain polyunsaturated alkamides which exert anti-inflammatory effects through inhibition of cyclooxygenase and 5-lipoxygenase. The polysaccharide portion has direct anti-inflammatory effects.

Indications:
◆ Prevention and treatment of common cold
◆ Recurrent infection of upper respiratory tract
◆ Bronchitis and cough

Dosage:
5-12 years – one tablet two times daily;
12 years and above – two tablets two times daily
for 7 – 14 days after meal

Side effects:
Allergic reaction has been reported but they are extremely rare and usually mild.
Transient tingling sensation on the tongue may be present.

Contraindication:
◆ Due to the potential for stimulating immune process and other over-reactive immune response, it is contraindicated in autoimmune diseases, collagen diseases and multiple sclerosis.
◆ It should not be exceeded a period of 8 successive weeks. It’s not suitable to use in TB and AIDS as a purpose of immunoenhancement.
◆ Under 2 years old, pregnancy and lactation

Combination therapy:
Because of immune stimulating effect, caution should be used in combining Echinacea with immunosuppressant drugs such as corticosteroids, cyclosporine, amiodarone, methotrexate and ketoconazole.

Quantity supplied:
10 tablets in one blister.
Two blisters per box.