Echinacold®

For acute respiratory tract infection

Echinacold

Composition:
Each tablet contains
Echinacea purpurea extract ……………… 300 mg
Piper betle extract ………………………………… 50 mg
Piper nigrum extract ……………………………. 50 mg
Zingiber officinale extract ………………….. 50 mg
Solanum indicum extract ………………….. 50 mg

Echinacea purpurea is the most potent ancient herbal medicine for natural immunity, anti-inflammatory and antiallergy. This plant also has some short term activity against influenza, herpes, vesicular stomatitis and other infectious microorganisms. This plant is cultivated in Shan State, Myanmar.

Pharmacological Actions:
1. Immunostimulating effect
Echinacold® stimulates the non-specific immune system, resulting an increase in phagocytosis. Arabinogalactan, a highly purified polysaccharides from the constituents of Echinacea is effective in activating macrophage cytotoxic actions against micro-organisms. In addition, the polysaccharides have an anti-hyaluronidase action thus may be lessened the spread of infectious agent in the body.

2. Antiviral effect
Echinacold® also has some short term viral resistance against influenza, herpes, vesicular stomatitis virus and others.

3. Anti-inflammatory effect
The constituents of Echinacea contain polyunsaturated alkamides which exert anti-inflammatory effects through inhibition of cyclooxygenase and 5-lipoxygenase.

Indications:
● Prevention and treatment of common cold
● Recurrent infection of upper respiratory tract
● Bronchitis and pertussis

Contraindications:
● Due to the potential for stimulating immune process and other over-reactive immune response, it is contraindicated in autoimmune diseases, collagen diseases and multiple sclerosis.
● Long term use of Echinacold® is restricted, so that it’s not suitable to use in TB and AIDS as a purpose of immunoenhancement.
● Pregnancy, lactating mother and children under 2 years

Side effects:
Allergic reaction has been reported but they are extremely rare and usually mild.
Transient tingling sensation on the tongue may be present.

Drug interaction:
Immune stimulating effect of Echinacold® may interfere with drugs that have immunosuppressant effects. It may also interfere with anticancer drugs such as cyclosporin and the cancer chemotherapeutic effect of corticosteroids. It can be used in combination with antibiotics of Western medicine.

Dosage:
12 years and above – two tablets two times daily
2-11 years – one tablet two times daily for 5 – 7 days after meal

Quantity supplied:
10 tablets in one blister.
Two blisters per box.

FAME Pharmaceuticals Industry Co., Ltd.
No. 20, Mingyi Mahar Min Gaung Road, Industrial Zone (3), Hlaing Thar Yar City of Industry, 11401, Yangon, Myanmar.
Office: +95 (1) 3685 083, 3682 199, 3685 609, Fax: +95 (1) 3680 122,
E-mail: sale@famepharma.com, drkml@famepharma.com

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