SawPalmetto

5α-reductase inhibitor

SawPalmetto
SawPalmetto

Composition:
Each tablet contains
Saw palmetto (Serenoa repens) berries extract …………. 160 mg

For many years, people took Saw palmetto to increase urine output in the form of a diuretic, or water pill. Some described Saw palmetto as the “old man’s friend”. In the early part of the twentieth century, Saw palmetto was commonly recommended for various prostatic conditions by healthcare professionals. Lipophilic extracts of Saw palmetto berries, rich in fatty acids and sterols are currently approved by medical scientists for treatment of BPH.

Pharmacological actions:
Anti-androgenic effect
Liposterolic Saw palmetto extract has been found to be an inhibitor of 5-alpha-reductase resulting in decreased dihydrotestosterone (DHT). It also competitively inhibits binding of testosterone and DHT to cytosolic and nuclear androgen receptors.
Anti-estrogenic effect
Anti-estrogenic effect of Saw palmetto is possibly due to competitively blocking translocation of cytosolic estrogen receptors to the nucleus.
Anti-inflammatory effect
Extracts of Saw palmetto have demonstrated anti-inflammatory activity. Inhibition of the synthesis of arachidonic acid inflammatory metabolites, through a double blocking of cyclooxygenase and 5-lipoxygenase pathways results in anti-inflammatory properties.

Indications:
◆ Benign prostatic hyperplasia (BPH)
◆ Inflammation of the urinary tract and urinary bladder
◆ Impotency, low libido
◆ Nocturnal enuresis

Dosage:
Adult men : one tablet two times daily after meal. It’s better to continue treatment although the signs and symptoms of BPH is relieved especially in men over 60 years.

Side effects:
Nausea and dizziness in some individuals

Contraindication:
Under 12 years old, pregnancy and lactating mother

Combination therapy:
Saw palmetto (SawPalmetto) can be used together with Bee pollen (BeePollen) in case of BPH, for obtaining their synergistic effect.

Drug interaction:
Saw palmetto is believed to exert estrogen, androgen and α-adrenergic blocking effects. Because of these effects,using hormone like drugs or adrenergic drugs concomitantly may need to be adjusted.

Quantity supplied:
60 tablets per bottle

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