SawPalmetto

5α-reductase inhibitor

SawPalmetto

Composition:
Each tablet contains standard extract of Saw palmetto (Serenoa repens) berries ……………………. 160 mg

For many years, people took Saw palmetto to increase urine output in the form of a diuretic, or water pill. Some described Saw palmetto as the “old man’s friend”. In the early part of the twentieth century, Saw palmetto was commonly recommended for various prostatic conditions by healthcare professionals. Lipophilic extracts of Saw palmetto berries, rich in fatty acids and sterols are currently approved by medical scientists for treatment of BPH.

Pharmacological Actions:
Anti-androgenic effect
The lipophilic extracts of Saw palmetto berries inhibit binding of DHT to the cytosolic androgenic receptor and α-1 adenoreceptors in the prostate thus preventing accumulation of steroids, which may lead to prostate hyperplasia.

Anti-estrogenic effect
Saw palmetto lowers cytosol and nuclear receptor values for estrogen which result in an anti-estrogenic effect since progesterone receptor content is linked to estrogenic activity.

Anti-inflammatory effect
Standard extracts of Saw palmetto have demonstrated anti-inflammatory activity. Inhibition of the synthesis of arachidonic acid inflammatory metabolites, through a double blocking of cyclooxygenase and 5-lipoxygenase pathways results in anti-inflammatory properties.

Indications:
● Prevention and treatment of BPH.
● Inflammation of the urinary tract and urinary bladder.
● Impotency, low libido.
● Nocturnal enuresis.

Drug interaction:
SawPalmetto can be used together with BeePollen in case of BPH, for obtaining their synergistic effect. Saw palmetto is believed to exert estrogen, androgen and α-adrenergic blocking effects. Because of these effects,using hormone like drugs or adrenergic drugs concomitantly may need to be adjusted.

Dosage:
Adult: one tablet two times daily after meal. It’s better to continue treatment although the signs and symptoms of BPH is relieved especially in men over 60 years. If not, the prostate gland may gradually enlarge and symptoms of BPH will appear again.

Quantity supplied:
60 tablets per bottle.

Copyright© 2019 FAME Pharmaceuticals Industry Co., Ltd. All rights reserved.