Composition:
Each capsule contains:
Valeriana officinalis and Valeriana wallichii root extract ………… 150 mg
Mimosa pudica extract ………………………………………………………………… 100 mg
Withania somnifera extract …………………………………………………………… 50 mg

Pharmacological actions:
Valeriana officinalis and Valeriana wallichii
Valerian has a long history of use in Western Europe as a sedative from Hippocrate’s time. The active compounds of valerian extract are valerenic acid and valepotriates. These compounds affect brain receptors for the neurotransmitter GABA, increasing GABA concentration and decreasing CNS activities. Several recent studies have shown that it reduces sleep latency and improves sleep quality.

Mimosa pudica
A number of clinical investigations have demonstrated that Mimosa pudica extract produces a calming effect in neurosis and induces sound sleep. It also has beneficial effects on several disorder parameters such as inner restlessness, frequency of waking and final wake time after sleep.

Withania somnifera
Withania somnifera is known to have anxiolytic, hypnotic and sedative effects and extensively used in India. This effect is contributed to the presence of alkaloid-somniferin. It relieves nervous exhaustion and promotes healthy sleep.

Indications:
◆ Insomnia
◆ Stress and anxiety
◆ Neuro-fatigue

Dosage:
Adult – one to two capsules one hour before going to bed as a sleep aid. It works better after regular use for insomnia.

Side effects:
Occasional headache and gastrointestinal distress

Caution:
Care should be taken when driving or operating heavy machinery. Alcohol can potentiate CNS depressant effects.

Contraindications:
Under 12 years old, pregnancy and lactation, patients with liver impairment, hypersensitivity to any constituent of the herbs

Combination therapy:
St. John’s wort (HerbalFresh^®) should be used in the morning to enhance efficacy of sleep.
Antioxidant supplement (Completec^®) should be taken daily to help productive sleep.

Quantity supplied:
60 capsules per bottle