Nephrotec®

Astragaloside IV

Nephrotec

Composition:
Each capsule contains:
Astragalus membranaceus root extract 300 mg containing astragaloside IV

Phytochemistry:
Its active components are flavonoids, poly- saccharides, triterpene glycosides (astragaloside I-VII), saponins and amino acids.

Scientific study:
Astragalus root extract improved renal function (serum creatinine decreased from 244±51 to 162±63 mmol/L; creatinine clearance increased from 37.8±6.2 to 53.4 ± 5.3 ml/min) as compared to the saline treated control group which was unchanged (Zhao et al., 2000). It had been as effective as ACEI captopril to improve renal function in patients with chronic renal failure (Yang et al.,1997).

Effect of Astragalus on proteinuria in nephrotic syndrome has been studied in clinical trials performed in China. Astragalus injection to patients with different forms of chronic glomerulonephritis had reduced proteinuria from 2328±3157 to 1017±765 mg/day (Shi et al.,2002). It also ameliorated the nephrotic syndrome related dyslipidemia in these trials (Wang et al.,2002).

It also improved water and sodium retention in the nephrotic syndrome. It attenuated the infiltration of inflammatory cells and promoted recovery from renal ischemia reperfusion injury in rats (Chen et al., 2001; Jang et al.,2003).

Pharmacological actions:
● Reduction of proteinuria
● Enhance remission of nephrotic syndrome
● Maintain stable levels of eGFR

Indications:
Chronic kidney diseases such as nephrotic syndrome, diabetic nephropathy, chronic glomerulonephritis and chronic renal failure

Dosage:
Children under 12 years – One capsule daily
12 years and above – One capsule two times daily in between meals.

Combination therapy:
Nephrotec® can be used together with Rejuvir®Caution:
If pregnant or breast-feeding, seek supervision from a physician before use.

Quantity supplied:
60 capsules per bottle.

FAME Pharmaceuticals Industry Co., Ltd.
No. 20, Mingyi Mahar Min Gaung Road, Industrial Zone (3), Hlaing Thar Yar City of Industry, 11401, Yangon, Myanmar.
Office: +95 (1) 3685 083, 3682 199, 3685 609, Fax: +95 (1) 3680 122,
E-mail: sale@famepharma.com, drkml@famepharma.com

Copyright© 2018 FAME Pharmaceuticals Industry Co.,Ltd. All rights reserved.