JavaHerb®

Anti-diabetic

JavaHerb
Product Description
Supplement Facts
Directions To Use

Pharmacological actions:
In vitro studies
1. Hypoglycaemic effect: In normoglycaemic rats, oral administration of an aqueous extract of O. aristatus (1g/kg) produces a significant decrease in blood glucose concentration compare with that in a control group.
2. Diuretic effect: In vitro and animal studies in rats have reported diuretic activity of extract of O. aristatus and of flavonoids (sinensetin and tetramethoxyflavone). Oral administration of methylripariochromene A (100 mg/kg) has been shown to increase urinary volume in fasted rats for three hours after oral administration.
3. Anti-hypertensive effect: In stroke-prone, spontaneously hypertensive rats, subcutaneous administration of methylripario-chromene A (100 mg/kg) produced a continuous reduction in systolic blood pressure and a decrease in heart rate. It also suppressed agonist-induced contractions in the rat thoracic aorta and decreased the contractile force in isolated guinea pig atria without significantly affecting the beating (heart) rate.

Clinical studies: A study involving 17 patients with type II Diabetes receiving 8 g of O. aristatus dried leaf in 250 ml boiled water for 30 mins, 3 times per day for 28 days was done in Department of Medical Research (Lower Myanmar). There was a statistically significant reduction of blood sugar level in these patients.

Composition:
Each tablet contains standard leaf extract of
Orthosiphon aristatus (Java tea) ………… 250 mg

Active constituents:
The active principles for controlling blood sugar are diterpenes. There are two groups of diterpenes: isopimarine-type (orthosiphones A and B, orthosiphols A, B, F, G, H and I) and pimarine-type (neoorthosiphols A and B). Other substances include saponins, alkaloids, tannin, essential oil, flavonoids, choline, betaine, organic acids and potassium salts.

Indication:

For prevention and treatment of type II Diabetes mellitus

Dosage: (Adult)
For prevention – one tablet daily before dinner
For treatment – one to two tablets two times daily half an hour before meal

Contraindication:
Pregnancy and lactating mothers

Quantity supplied:
60 tablets per bottle

FAME Pharmaceuticals Industry Co., Ltd.
No. 20, Mingyi Mahar Min Gaung Road, Industrial Zone (3), Hlaing Thar Yar City of Industry, 11401, Yangon, Myanmar.
Office: +95 (1) 685 083, 682 199, 685 609, Fax: +95 (1) 680 122, E-mail: sale@famepharma.com

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