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Hepaforte

NORMOSINฎ
(Anti-hypertensive agent)
Hypertension is a world-wide problem affecting
millions of people. In Myanmar, hypertension is also affecting about
23% of population with the age of 20 years and over. Newly occuring
hypertensive cases are increasing year by year because of changing
life style.
If hypertension is not treated properly and effectively,
complications and sequelae of hypertension will occur. Hypertension
will accelerate the atherosclerotic process in the blood vessels of
all organs of the body especially brain, heart and kidneys which
will result in insufficient blood flow to these organs. Finally, it
will cause stroke, heart attack, heart and kidney failure, and
death. Therefore, hypertension could be regarded a silent killer.
Although, hypertension has been conventionally treated with Western
antihypertensives, patients fail to comply with them because of
their considerable side-effects in the long-run. Therefore, FAME
Pharmaceuticals is now producing Normosin for treating hypertension,
which is scientifically developed with reputed natural herbs.
Composition
Each tablet contains:
Plantago major extract ................................ 60 mg
Moringa oleifera extract .............................. 60 mg
Arundo donax extract ................................... 40 mg
Terminalia arjuna extract ............................. 20 mg
Allium sativum extract ................................. 20 mg
Pharmacological actions
Plantago major : Grows wild in
Shan and Kachin States, Myanmar. Leaves contain glucosides, saponins
and bitter compounds. Seeds contain 0.183% holoside planteose. Plant
contains glucoside aucubin. Ursolic acid, N-hentriacontane, steryl
ester and b-sitosterol were isolated from the whole plant.
Homoplantaginin, a new flavonoid glycoside is also present in the
leaves.
Moringa oleifera : It is
cultivated in gardens for its edible fruits throughout Myanmar.
Alkaloid and gum present in the plant. Alkaloid moringine and
moringinine is isolated from the root bark of the plant.
Pterygospermin present in the roots is an oily substance with a
reddish brown colour and highly piercing smell. Flowers contain
amorphous base.
Arundo donax : Root of Arundo
donax is composed in many herbal diuretics so that decreases the
blood pressure. Especially, it is used for urolithiasis, cystitis,
dysuria and other urinary disorders.
Terminalia arjuna : Arjuna is
beneficial for angina and poor coronary circulation. It is alos
beneficial if the hearts rate and rhythum are abnormal. By lowering
blood cholesterol levels, reducing blood pressure, and supporting
normal heart function. Arjuna improves the health of the circulation
and reduces the risk of developing a serious heart problem. A
traditional Ayruvedic botanical for cardiac failure has recently
been shown to be very effective in a controlledd clinical study.
Allium sativum : Clinical trials
have confirmed that garlic reduces blood cholestrol level and lowers
blood pressure. According to studies, It has been shown to decrease
systolic pressure by 20-30 mmHg and diastolic pressure by 10-20 mmHg
in people with high blood pressure. If the blood pressure lowering
effects of garlic can be maintained, the risk of stroke may be
reduced by 30-40% and the risk of heart attack by 20-50%. The
ability of this combination is to increase the control rate in
hypertension and to prevent the development of complication.
Indication
Treatment of Hypertension
Dosage
Blood pressure
Grading |
Age
(Years) |
Blood Pressure
(Systolic/Diastolic) |
Dosage |
Daily
Regimen |
Method of
Administration |
Mild
hypertension |
20 50 |
|
One tablet |
Once |
Half-an-hour
before meal |
Moderate
hypertension |
20
50 |
|
Between 140/90 and 160/100 |
|
Between 160/95 and 170/110 |
|
One tablet |
Twice |
Half-an-hour
before meal |
Severe
hypertension |
20
50 |
|
Above 160/100 |
|
Above 170/110 |
|
One tablet |
Thrice |
Half-an-hour
before meal |
Side effects
None in recommended dose.
Caution:
Children under 12 years, pregnancy and lactating
mother should be only used under the supervision of physician.
How supply:
30 tablets per bottle.
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