GynuHerb®

Natural medicine for diabetes

GynuHerb

Composition:
Each capsule contains:
Organic Gynura procumbens air dried leaf powder ………………….. 300 mg

Active Constituents:
Gynura procumbens contains phytosterols (β-sitosterol and stigmasterol), sterol glycosides (3-O-β-D-glucopyranosyl β-sitosterol, 3-O-β-D-glucopyranosyl stigmasterol), nonadecane, phytyl valerate, adenosine, kaempferol-3-O-neohesperidoside, methyl hexa- decanoate, methyl 9-octadecenoate, 4-hydroxy-4-methyl-2-pentanone, stigmasterol acetate, quercetin-O-caffeoylquinic acid, 1, 2-bisdodecanoyl-3-α-O-D-glucopyranosyl-Sn-glycerol.

Pharmacological actions:
1. Conversion of glucose to vitamin C

Humans are one of the few species who lack the enzyme to convert glucose to vitamin C. According to the scientific study, Gynura procumbens leaves are rich in enzymes and coenzymes which have ability to convert glucose to vitamin C in vitro. By taking orally it may transform plasma glucose to ascorbic acid inside our body.

2. Anti-diabetic Action
The ethanol extract of Gynura procumbens was reported to have anti-hyperglycemic and anti-hyperlipidemic activities in diabetic rats. The extract of Gynura procumbens leaves may have biguanide-like activity. The extract showed similar effect to metformin by improving glucose tolerance (OGTT) in STZ-induced diabetic rats. The methanol extract and n-butanol fraction exerted a significant hypoglycemic effect when administered orally to streptozotocin-induced diabetic rats. The leaf extract of G. procumbens significantly reverses the adverse effects of elevated accumulation of intracellular glucose. It may have therapeutic potential for the treatment of diabetic retinopathy.

3. Anti-hypertensive action
Gynura procumbens extract (GPE) administered rats had significantly lower serum lactate dehydrogenase, creatine phosphokinase and increased nitric oxide, a known vasodilator and decreased the systolic & diastolic blood pressure. Glycoconjugated or peptidal substances found in GPE that exhibit an inhibitory effect on ACE. It is useful for prevention and treatment of hypertension through increasing nitric oxide production in blood vessels.

Indications:
● Diabetes mellitus
● Diabetic retinopathy & nephropathy
● Hypertension
● Hyperlipidemia & hypercholesterolemia

Combination Therapy:
It can also be used together with DiabeHerb® and JavaHerb® for more effective treatment.

Dosage:
Adult : one to two capsules two to three times daily half-an-hour before meal

Caution:
● To adjust the dosage of other hypoglycemic agent when use together with GynuHerb®.
● If pregnant or breast-feeding, seek supervision from a physician before use.

Quantity supplied:
60 capsules per bottle

FAME Pharmaceuticals Industry Co., Ltd.
No. 20, Mingyi Mahar Min Gaung Road, Industrial Zone (3), Hlaing Thar Yar City of Industry, 11401, Yangon, Myanmar.
Office: +95 (1) 3685 083, 3682 199, 3685 609, Fax: +95 (1) 3680 122,
E-mail: sale@famepharma.com, drkml@famepharma.com

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