Cholecrush®

For gallstones

Cholecrush

Composition:
Each caplet contains:
Silybum marianum extract ………………… 160 mg
Eclipta alba extract ……………………………… 120 mg
Picrorhiza kurroa extract …………………… 100 mg
Soy lecithin ……………………………………………. 80 mg
Emblica officinalis powder …………………. 40 mg

Pharmacological Actions:
● dissolves gallstones
● inhibits cholesterol synthesis in liver
● reduces cholesterol concentration in the bile
● increases production of bile in liver
● more solubility of ingredients in bile
● maintains fluidity of bile
● reduces inflammation in biliary tract
● prevents further formation of gallstones

Silybum marianum – Milk thistle contains the active compound known as silymarin which may help to prevent or treat gallstones via its ability to increase the solubility of the bile. It also reduces biliary cholesterol concentration and bile saturation index, thus helping to dissolve gallstones and eliminates stones that may have formed.

Eclipta alba – It contains a number of active principles such as wedelolactone, stigmasterol, β-sitosterol, and alkaloid ecliptine. They enhance liver function in fatty liver and cirrhosis. They also make the cholesterol more dissolved in the bile to prevent precipitation.

Picrorhiza kurroa – Picroliv, an iridoid glycoside mixture from Picrorhiza kurroa, reduces cholesterol levels by inhibiting an enzyme, HMG Co-A reductase, which is involved in the production of cholesterol in the liver. Low level of cholesterol in the bile may help to dissolve gallstones and prevent further stones formation.

Soy Lecithin – Soy lecithin is a natural fat emulsifier. It is a phospholipid composed of phosphatidyl esters, one of which is phosphatidylcholine. Inadequate level of lecithin may precipitate gallstones. Phospholipids increase the solubility of biliary cholesterol. Lecithin and bile salts reduce the saturation of cholesterol in the bile that leads to stone formation.

Emblica officinalis – Natural vitamin C is important because it lowers bile cholesterol levels, decreasing the chance that cholesterol-laden bile will clump to form gallstones.

Indications:
● Cholelithiasis (gallstones)
● Cholecystitis and cholangitis
● Prophylatic treatment of recurrence of gallstones

Dosage:
12 years and above : one caplet three times daily half an hour before meal
Children 6-12 years : half caplet three times daily half an hour before meal
Duration of treatment depends upon type, size, number and duration of gallstone formation.

Contraindications:
Pregnancy and lactation

Combination therapy:
Antibiotics may be used in combination with Cholecrush® in case of cholecystitis and cholangitis.
It is beneficial to take together with Vitamin C and Omega-3 fatty acid supplement.

Quantity supplied:
60 caplets per bottle

FAME Pharmaceuticals Industry Co., Ltd.
No. 20, Mingyi Mahar Min Gaung Road, Industrial Zone (3), Hlaing Thar Yar City of Industry, 11401, Yangon, Myanmar.
Office: +95 (1) 3685 083, 3682 199, 3685 609, Fax: +95 (1) 3680 122,
E-mail: sale@famepharma.com, drkml@famepharma.com

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